目的:探讨女性生殖道解脲支原体(UU)感染情况,并对耐药性结果进行检测分析。方法:收集近期在该院妇科诊治的疑似UU感染病例246例女性。检测其生殖道解脲支原体感染情况,并分析UU阳性标本抗生素耐药性检测结果。结果:79例UU阳性标本对9种常用抗生素的药敏试验显示克拉霉素(79.7%)对UU敏感最强,其后依次是强力霉素(74.7%)和美满霉素(72.2%)。耐药发生率依次为氧氟沙星(40.5%)、左氧氟沙星(36.7%)和交沙霉素(31.6%)。结论:解脲支原体是导致非淋菌性尿道(宫颈)炎等女性生殖系统疾病的最重要致病菌,应依据药物敏感试验确定治疗药物。 Objective: To investigate the female genital Ureaplasma urealyticum (UU) infection, and drug resistance results were analyzed. Methods: A total of 246 women with suspected UU infection were collected from a gynecological clinic in the hospital recently. Urogenital Ureaplasma urealyticum genital tract infection was detected, and UU positive specimens antibiotic resistance test results. Results: The susceptibility tests of 9 UU positive samples to 9 commonly used antibiotics showed that clarithromycin (79.7%) was the most sensitive to UU, followed by doxycycline (74.7%) and minocycline (72.2%). The resistance rates were ofloxacin (40.5%), levofloxacin (36.7%) and jasmomycin (31.6%). Conclusion: Ureaplasma urealyticum is the most important causative agent of female reproductive system diseases such as non-gonococcal urethritis (cervix). Drugs should be determined according to drug sensitivity test.