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随着脑磁图(MEG)在临床应用的不断发展,其在神经疾病的诊治中发挥着越来越大的作用。除了在顽固性癫痫患者术前致痫灶定位方面具有一定的作用外,它在脑肿瘤的外科治疗中也起到一定的指导作用,尤其是当肿瘤位于脑功能区时。脑肿瘤外科术前通过应用MEG定位大脑皮层的感觉、运动和语言功能区(PSFM)的方法明显优于fMRI和术中电刺激,同时它还可以指导脑肿瘤微创外科手术,并有助于手术方式的选择及判断预后。将PSFM结果与导航系统相结合,可以避免在手术中损伤重要的功能区,提高了患者术后的生活质量。对于那些脑肿瘤伴有癫痫的患者,术前除了可以进行功能区定位外,它还可以明确肿瘤与癫痫的关系,从而指导外科手术治疗。
With the continuous development of magnetoencephalography (MEG) in clinical application, it plays an increasingly important role in the diagnosis and treatment of neurological diseases. In addition to its role in preoperative localization of epileptogenic lesions in patients with refractory epilepsy, it also plays a guiding role in the surgical treatment of brain tumors, especially when the tumor is located in the brain’s functional area. Brain Tumor Surgery Preoperative localization of cerebral cortex sensory, locomotor, and speech functional areas (PSFMs) by using MEG is significantly better than fMRI and intraoperative electrical stimulation and it can also guide minimally invasive surgery in brain tumors and contribute to Surgical options and prognosis. Combining the results of PSFM with the navigation system can avoid the damage of important functional areas during surgery and improve the postoperative quality of life of the patients. For those patients with brain tumors associated with epilepsy, preoperative addition to the functional area can be located, it can also clear the relationship between tumor and epilepsy, which guide the surgical treatment.