论文部分内容阅读
目的通过分析4例艾滋病合并奴卡菌病患者的临床资料并复习相关文献,提高对该病的认识。方法回顾性分析云南省传染病专科医院2014年6月至2015年6月确诊艾滋病合并奴卡菌病患者的临床资料,复习相关文献。结果 4例患者均为男性,年龄29~57岁,CD4~+T淋巴细胞计数4~97个/μL。4例患者均有发热,体表多发脓肿3例。4例患者中,播散性奴卡菌病3例,肺奴卡菌病1例。发热并发难治性肺部感染,胸部CT呈单个或多发结节阴影伴空洞。除1例患者在确诊奴卡菌病前死亡外,3例采用磺胺联合其他药物治疗,2例好转,1例死亡。结论对于艾滋病病毒感染者/艾滋病患者,尤其皮下有多发脓肿时,应及时进行奴卡菌病相关检查,尽早确诊,尽早治疗。
Objective To improve the understanding of the disease by analyzing the clinical data of 4 AIDS patients with concomitant cardiomyopathy and reviewing the relevant literature. Methods Retrospective analysis of clinical data of Yunnan Province Infectious Diseases Hospital from June 2014 to June 2015 confirmed AIDS patients with concomitant carderculosis disease, review the relevant literature. Results All 4 patients were male, aged from 29 to 57 years old, with CD4 ~ + T lymphocyte counts from 4 to 97 / μL. 4 patients had fever, multiple abscesses on the surface in 3 cases. Among the 4 patients, 3 were disseminated venereal disease and 1 was pulmonary concomitant cardiomyopathy. Fever complicated with refractory pulmonary infection, chest CT showed a single or multiple nodular shadow with empty hole. Except for one patient died before the diagnosis of nocardiosis, three patients were treated with sulfa combined with other drugs, two patients improved and one patient died. Conclusions For patients with HIV / AIDS, especially those with multiple subcutaneous abscesses, the related diagnosis of nocardiosis should be promptly carried out. The patients should be diagnosed as soon as possible and treated as soon as possible.