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树突状细胞是最有效力的免疫反应的刺激剂。作者用转移性肾癌病人的树突状细胞与抗原培养,进行初步实验研究。取术后4周肾癌病人的150ml外周血,用GMCSF和IL4培养5天后获得树突状细胞,在第5天时用培养的自体肿瘤细胞溶解产物包被树突状细胞,用KLH...
Dendritic cells are the most potent immune response stimulators. The authors used dendritic cells from patients with metastatic renal cell carcinoma and antigen culture, preliminary experimental study. Dendritic cells were obtained from 150 ml of peripheral blood from patients with kidney cancer at 4 weeks after surgery and dendritic cells were cultured with GMCSF and IL-4 for 5 days. On Day 5, dendritic cells were coated with the autologous tumor cell lysate and treated with KLH. ..