目前已证实,克隆氏病初期主要损害回肠末端粘膜,随着病情的发展,病变可扩展到包括口腔粘膜在内的整个胃肠道。作者在2年内检查了40名克隆氏病患者,其中6例(男5,女1)发现有口腔粘膜损害。2例在出现胃肠道克隆氏病表现前1.5～2年,先出现口腔粘膜损害被诊为“溃疡性口腔炎”,按口腔炎治疗无效。其余4例的口腔粘膜损害出现在胃肠道病变发生后5～6年。口腔克隆氏病的临床表现具有一定的特点,按其病理过程可分为3型,水肿型、溃疡型、假息肉型。在作者 It has been confirmed that the early stage of Crohn’s disease mainly damage the terminal ileal mucosa, with the progression of the disease can be extended to include the entire gastrointestinal tract, including oral mucosa. The authors examined 40 patients with Crohn’s disease within 2 years, 6 of whom (male 5, female 1) found oral mucosal damage. 2 cases of gastrointestinal Crohn’s disease before the performance of 1.5 to 2 years, the first occurrence of oral mucosal damage was diagnosed as “ulcerative stomatitis”, stomatitis treatment ineffective. The remaining four cases of oral mucosal damage occurred in gastrointestinal lesions 5 to 6 years after. The clinical manifestations of oral Crohn’s disease has certain characteristics, according to the pathological process can be divided into 3 types, edema, ulceration, false polyp type. At the author