论文部分内容阅读
前言 环糊精(CD)分子由于其独特的洞穴结构可与许多物质形成包含复合物,因而在色谱过程中对许多化合物具有选择性的保留作用,现已被用作气相、液相及薄层色谱的固定相,尤以液相色谱的研究最为活跃。液相色谱领域的研究报道表明β-环糊精可被广泛用于分离对映体、非刘映体和结构异构体等各类化合物。有人曾将环糊精通过一个含氮的空间基团与硅胶键合起来,但实践证明这种高效液相色谱填料易水解,柱效低,合成过程也太长。Armstrong等人合成了
Preface Cyclodextrin (CD) molecules, due to their unique cave structure, can form inclusion complexes with many substances and thus have a selective retention of many compounds during the chromatography process and have now been used as gas, liquid and thin layers Chromatography of the stationary phase, especially in the most active liquid chromatography. Studies in the field of liquid chromatography show that β-cyclodextrin can be widely used for the separation of various compounds such as enantiomers, non-enantiomers and structural isomers. Cyclodextrin has been linked to silica by a nitrogen-containing space group. However, it has been proved that this high performance liquid chromatographic packing is easy to hydrolyze and has low column efficiency and long synthesis time. Armstrong et al