淀粉样变性多见于人体脏器及皮下,仅限于口腔颌面部者少见,现将本科诊治的一例报告如下。患者女性,51岁。因口底、双颌下无痛性肿块,舌体进行性肥大伴吞咽困难,语言不清8月余入院。3月前发现双颌下、颏部有核桃大小肿物,活动度较差,无红肿热痛。继之口底及舌体逐渐肥大,偶有灼热感。舌体活动受限,发音不清,吞咽困难,味觉迟钝,屡被咬伤。当地医院诊断为口底蜂窝织炎,经抗生素治疗无效, Amyloidosis more common in human organs and subcutaneous, limited to oral and maxillofacial rare, now a case of undergraduate diagnosis and treatment are reported as follows. Patient female, 51 years old. Due to the mouth, bilaterally painless mass, tongue hypertrophy with dysphagia, language unclear in August more than admitted. 3 months ago found double jaw, chin size walnut tumor, poor activity, no swelling and pain. Following the mouth and tongue gradually hypertrophy, occasionally burning sensation. Tongue activity is limited, unclear pronunciation, swallowing difficulties, slow taste, repeated bitten. Local hospital diagnosis of mouth cellulitis, antibiotic treatment ineffective,