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为研究非甾体抗炎药致上消化道损伤的临床诊治，回顾性分析确诊的65例病例资料．结果表明，50岁以上为高发年龄，男性多子女性，以突发上消化道出血为主要表现（75．4％）部分患者伴有上腹痛、烧灼感（24.6％）．出血轻重程度与年龄及药物种类无关，多在服药后3天-5天出现症状，内镜下病变包括粘膜充血、水肿、糜烂、浅表溃疡．抑酸治疗效果良好，提示非甾体抗炎药引起的消化道损伤较为常见，需服用非甾体抗炎药患者可考虑加用粘膜保护剂或抑酸剂．
In order to study the clinical diagnosis and treatment of upper gastrointestinal tract injury induced by NSAIDs, 65 confirmed cases were retrospectively analyzed. The results showed that some patients were accompanied by upper abdominal pain and burning sensation (24.6%) in those over 50 years old with high age, male multiple children and sudden upper gastrointestinal bleeding (75.4%). Bleeding severity and age and type of drug has nothing to do, and more in 3 days after taking the medicine -5 days symptoms, endoscopic lesions including mucosal congestion, edema, erosion, superficial ulcers. Inhibition of acid treatment is good, suggesting that non-steroidal anti-inflammatory drugs caused by digestive tract damage is more common, patients taking non-steroidal anti-inflammatory drugs may consider adding mucosal protective agent or acid-suppressing agent.