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目的:探讨妊娠期糖尿病及糖耐量受损对妊娠结局的影响。方法:2008年1月~2009年5月在该院进行产前检查,确诊妊娠期糖尿病(GDM)103例,妊娠期糖耐量受损(GIGT)90例,选择同期分娩100例健康孕妇为对照组,比较三组的妊娠结局。结果:GDM1组(治疗组)及GIGT组仅剖宫产率、巨大儿发生率明显高于正常组,差异有统计学意义(P<0.05),妊娠期高血压疾病、胎膜早破、羊水过多、胎儿窘迫、早产、新生儿低血糖与正常组比较差异无统计学意义(P>0.05);GDM2组(未治疗组)母儿并发症的发生率明显高于其他各组,差异有统计学意义(P<0.05)。结论:GDM与GIGT是导致母婴近期远期严重并发症的重要因素,临床医师应重视孕期糖代谢异常的筛查、诊断和治疗,尽可能使孕妇血糖控制在正常范围。
Objective: To investigate the impact of gestational diabetes mellitus and impaired glucose tolerance on pregnancy outcome. Methods: From January 2008 to May 2009, 103 prenatal tests of gestational diabetes mellitus (GDM), 90 cases of impaired glucose tolerance (GIGT) in pregnancy were performed in this hospital. 100 healthy pregnant women of the same period were selected as control Group, comparing the three groups of pregnancy outcomes. Results: Only the rate of cesarean section and the incidence of macrosomia in GDM1 group and GIGT group were significantly higher than those in normal group (P <0.05), hypertensive disorders in pregnancy, premature rupture of membranes, amniotic fluid Excessive fetal distress, premature delivery, neonatal hypoglycemia and normal group was no significant difference (P> 0.05); GDM2 group (untreated group) the incidence of maternal and child complications was significantly higher than the other groups, the difference was Statistical significance (P <0.05). Conclusion: GDM and GIGT are the important factors leading to serious long-term complications in both maternal and neonates. Clinicians should pay attention to the screening, diagnosis and treatment of abnormal glucose metabolism during pregnancy, and should control the blood glucose of pregnant women in the normal range as much as possible.