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目的:采用液基薄层细胞制片技术(TCT)结合组织活检术检测、诊断和评价宫颈病变,特别是癌前病变的程度及所处的状态,为临床合理治疗宫颈病变提供准确依据,观察治疗后的效果。方法:运用TCT连续3年检测了10 212例妇女,包括457例应城市人民医院女职工。细胞学诊断按TBS标准。对TCT部分阳性者进行宫颈活检。结果:10 212例妇女中,细胞学阳性(ASC-UC以上)391例,阳性率为3.83%,其中ASC-UC 296例(2.90%)、ASC-H 85例(0.84%)、LSIL 5例(0.05%)、HSIL 3例(0.03%)、SCC 1例(0.01%)、AGC 1例(0.01%)。应城市人民医院457例女职工连续3年细胞学筛查的阳性率为3.42%、0.88%和0.00%。结论:TCT对宫颈病变筛查及妇科治疗后疗效观察有很大的优越性,配合宫颈活检及治疗能显著降低宫颈病变的发生和发展,具有重要的临床应用价值。
OBJECTIVE: To detect, diagnose and evaluate the degree of cervical lesions, especially precancerous lesions and their status by using liquid-based thin-layer cell technique (TCT) combined with tissue biopsy, to provide an accurate basis for clinical treatment of cervical lesions and to observe After treatment effect. Methods: A total of 10 212 women, including 457 women workers in Yingcheng People’s Hospital, were tested for three consecutive years by TCT. Cytological diagnosis by TBS standards. Cervical biopsy of TCT-positive. Results: The positive rate of ASC-UC was 391 in 10 212 women, including 296 cases (2.90%) of ASC-UC, 85 cases (0.84%) of ASC-H and 5 cases of LSIL (0.05%), 3 cases of HSIL (0.03%), 1 case of SCC (0.01%) and 1 case of AGC (0.01%). Yingcheng People’s Hospital, 457 female workers for 3 consecutive years cytology screening positive rate was 3.42%, 0.88% and 0.00%. Conclusion: TCT screening of cervical lesions and gynecological treatment has great advantages in observation, with cervical biopsy and treatment can significantly reduce the occurrence and development of cervical lesions, has important clinical value.