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用大剂量抗栓酶—3(Svate—3)0.07μ/kg(28usp/kg)加2%普鲁卡因0.8ml/kg(0.016g/kg),经狗颈动脉注射30分钟,观察其行为36小时后处死。结果未发现其行为和脑组织病理学的明显异常。作者认为大剂量注射这些药物是安全的,可酌情减量试用于临床治疗脑梗塞。
With a large dose of antithrombotic enzyme-3 (Svate-3) 0.07μ/kg (28usp/kg) plus 2% procaine 0.8ml/kg (0.016g/kg), the dog carotid artery injection for 30 minutes to observe its Behavior was executed after 36 hours. No significant abnormalities in its behavior and brain histopathology were found. The authors believe that high-dose injections of these drugs are safe and can be reduced to trials for clinical treatment of cerebral infarctions, as appropriate.