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对163例非胰岛素依赖型糖尿病(NIDDM)患者口服葡萄糖。胰岛素释放试验(OGIRT)结果作回顾性分析。根据各时相胰岛素释放和血糖关系的特点,将其归纳为四型,即同步型,迟后型,超前型和无反应型。分析了各型特点及各型年龄,病程、体重指数、HbA1因素间的关系。结果表明NIDDM的胰岛素β细胞对葡萄糖反应变异很大。对于无反应型应在OGIRT基础上采用胰高糖素-胰岛素释放试验,以进一步了解胰岛β细胞分泌功能。
163 patients with non-insulin-dependent diabetes mellitus (NIDDM) were given oral glucose. Insulin release test (OGIRT) results for retrospective analysis. According to the characteristics of the relationship between the release of insulin and blood glucose at each time, it is classified into four types, namely synchronous type, late type, advanced type and non-responsive type. The characteristics of each type and the relationship among various types of age, course of disease, body mass index and HbA1 were analyzed. The results show that NIDDM’s insulin-β cells vary widely in glucose response. For nonresponders OGIRT should be based on the use of glucagon - insulin release test to further understand the pancreatic β-cell secretory function.