A targeting liposomal structure by incorporating vincristine with dasatinib for treatment of invasiv

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户:djdyaqb
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Recurrence of invasive breast cancer could arise from the residual cancer cells after comprehensive treatment.The residual cancer cells are able to form highly patterned vasculogenic mimicry (VM) channels,finally leading to the relapse and metastasis of cancers.In the present study, a new type of targeting vincristine plus dasatinib liposomes was developed for elimination of invasive cancer cells along with the VM channels.
其他文献
Colloidosomes are microcapsules that consist of a hollow core coated by a shell composed of self-assembled colloidal particles.In recent years, they have attracted significant attention for the contro
Objective:To optimizate the membrane cleaning process of 0.2 μm Al2O3 ceramic membrane microfiltration of the Compound Banlangen Liyan Granules water extraction liquid.Method:According to the index of
The design of targeted polymer-drug conjugate capable of controlled drug release remains a benchmark for drug delivery systems.Although numerous polymer-drug conjugates exhibiting substantial drug-loa
Clinically, paclitaxel (PTX) is one of most commonly prescribed therapies against a wide range of solid neoplasms.Despite its success, the clinical applicability of PTX (Taxol(R)) is severely hampered
Over the past decades, due to the unique advantages of nanoparticles over small molecules, nanomedicine has offered new strategies for cancer treatment.Understanding the interdependence of the physioc
会议
Herein, a redox sensitive hyaluronic acid-decorated graphene oxide (HA-ss-GO) has been successfully synthesized as a novel functionalized tumor targeting drug delivery system for atntineoplastic drug,
Purpose: To synthesize pH-responsive single-walled carbon nanotubes (SWCNTs) loading survivin siRNA, and to characterize the physicochemical properties and evaluate the cytotoxicity of nanocarriers.Me
In order to examine the effect of capsaicin in the regulation of P-gp substrate rhodamine 123(R123)across the intestinal membranes, the permeability of R123 or fluorescein sodium(CF) via jejunum, ileu
The purpose of this work was to establish a novel polymeric drug delivery system with functions of long circulation, active targeting, redox and pH dual responsive drug release.G4 Poly(amidoamine)dend
In our previous study, we can delivery drug to specific issues and cells.However, the problems of drug release in tumor cells and intracellular drug process cannot be solved So we have developed a chi