stemness相关论文
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulatin
Pancreatic cancer (PC) is one of the most deadly diseases,and its incidence is increasing year by year.The methyltransfe......
TUSC3 induces chemotherapy resistance and cellular stemness via Hedgehog signaling pathway in colore
Objective Cancer stem cells(CSCs) and chemotherapy resistance are the major causesthat induce recurrence and metastasis ......
Objective PURPOSE:To examine the role of miR-106b-5p in regulating the cancer stem-cell-like phenotype in clear cell ren......
Metastasis-related miR-30c/e suppresses cancer stemness by targeting LRP6in hepatocellular carcinoma
目的 Hepatocellular carcinoma(HCC)is an aggressive cancer with a dismal outcome largely due to metastasis and postsurgic......
ES Micro-Environment Enhances Stemness and Inhibits Apoptosis in Human Limbal Stem Cells via the Mai
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The negative costimulatory molecule B7-H3 promotes tumor stemness and metastasis via induction of ep
Introduction: Colorectal cancer is a serious threat to human health.And metastasis is the key factor of poor prognosis.R......
Pristimerin inhibits prostate cancer bone metastasis by targeting PC-3 stem cell characteristics and
Prostate cancer (PCa) is one of the most common malignant cancers and a major leading cause of cancer deaths in men.Canc......
Identification of stemness of primary retinoblastoma cells by stem cell markers,phenotype,and tumori
Objective Retinoblastoma(RB)is the most common intraocular malignancy in childhood,representing 2.5%to 4%of all pediatri......
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目的探讨肝细胞核因子4γ(HNF4γ)在胃癌细胞增殖和干性维持中的作用及机制。方法收集2012—2015年在郑州大学第一附属医院行胃癌......
Previously regarded as simple fat storage particles,new evidence suggests thatlipid droplets(LDs)are dynamic and functio......
The classical cancer stem cell(CSCs)theory proposed the existence of a rare but constant subpopulation of CSCs.In this m......
Stemness and Chemotherapeutic Drug Resistance Induced by EIF5A2 Overexpression in Esophageal Squamou
Esophageal squamous cell carcinoma(ESCC)is one of the most lethal malignancies of the digestive tract in East Asian ......
目的:探讨长链非编码RNA KCNQ1DN在尿源干细胞干性调控中的作用。方法:收集健康成人(n=6)尿液,提取尿源干细胞并传代培养,分别收集......
The relationship of carcinogenesis and DNA methyltransferases has attracted extensive attention in tumor research.We rep......
The Three-Dimensional Collagen Scaffold Improves the Stemness of Rat Bone Marrow Mesenchymal Stem Ce
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Micro RNAs(mi RNAs) are a class of non-coding RNAs that are believed to have a significant role in tumorigenesis and can......
microRNAs(miRNAs)是一类非编码的小RNA,在肿瘤发生发展及侵袭转移中发挥着至关重要的作用.肿瘤干细胞是导致恶性肿瘤复发、转移和......
目的探讨B7-H4表达对胃癌患者预后的影响及其可能机制。方法利用UALCAN、Kaplan-Meier Plotter数据库及GEPIA在线分析工具分析胃癌......
目的:探讨miR-612对肝细胞癌(HCC)干细胞特性的影响并探讨其机制。方法:采用实时定量PCR(qRT-PCR)法检测miR-612在HCC细胞系和正常......
目的:探究睾丸相关的高保守的致癌长链非编码RNA(THOR)在胃癌细胞中的表达及对胃癌细胞干性的影响。方法:收集徐州医科大学附属医......
随着高通量技术的发展和表观遗传学的深入研究,人们发现基因组大量的非编码RNA(noncoding RNA,ncRNA)转录本,其能从基因组上转录而......
目的：比较人根尖牙乳头干细胞（SCAP）与非干细胞（非SCAP）之间差异表达的miRNAs,并进行功能预测分析。方法：采用酶消化法获得原代人根尖牙......
Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal ca
AIM To find the mechanisms by which special AT-rich sequence-binding protein 2(SATB2) influences colorectal cancer(CRC) ......
Despite their potential applications in future regenerative medicine, periodontal ligament stem cells(PDLSCs) are diffic......
目的考察槲皮素对缺氧诱导的乳腺癌细胞增殖及干性的影响。方法缺氧诱导剂CoCl2体外培养BT549和MDA-MB-231细胞模拟缺氧微环境体系......
目的:研究miR-125a在口腔鳞状细胞癌(FOSCC)组织中的表达及与OSCC患者临床病例特征的关系,并探讨miR-125a对E2F2的靶向调控作用和......
BACKGROUND Mesenchymal stem cells are pluripotent cells that have the ability to generate cells from a cell line or in o......
Pluripotent stem cells are unspecialized cells withunlimited self-renewal, and they can be triggered todifferentiate int......
GBM Cancer stem cells (CSCs) are responsible for growth, recurrence and resistance to chemo- and radio-therapy. They are......
GBM Cancer stem cells (CSCs) are responsible for growth, recurrence and resistance to chemo- and radio-therapy. They are......
Circulating tumor cells (CTCs) are a population of tumor-derived cells that detach from the primary tumor and initiate m......
Circulating tumor cells (CTCs) are a population of tumor-derived cells that detach from the primary tumor and initiate m......
Bile acids(BAs)are cholesterol derivatives synthesized in the liver and then secreted into the intestine for lipid absor......
目的:程序性死亡受体-配体1(Programmed death-ligand 1,PD-L1)的表达是导致胃癌免疫逃逸的主要原因之一,然而,调控胃癌细胞PD-L1......
Carcinogenic process has been proposed to relay on the capacity to induce local tissue damage and proliferative repair. ......
The cancer microenvironment has been reported to have a significant impact on cancer cells in many ways.Indeed,in such a......
MicroRNA-regulated cancer stemness in the patient-derived xenograft model of human cholangiocarcinom
Objective:MicroRNAs(miRNAs)are highly conserved 19-25 nucleotide small noncoding RNAs,which are primarily involved in ge......
