phospholamban相关论文
Peroxiredoxin Ⅱ, an anti-oxidant protein, is a new regulator of cardiac contractility through phosph
Aim: Peroxiredoxin Ⅱ (prxⅡ), a cytosolic form of the anti-oxidant peroxiredoxin family, has been reported to protect c......
Adeno-Associated Virus 2/1-Based RNA Interference:Ablation of Phospholamban Improve Cardiac Function
Objective:to investigate the efficacy of the RNAi method for ablation of PLB gene expression and improvement SERCA2a act......
目的 探讨心肌内质网Ca^2＋调控蛋白表达与心肺复苏（CPR）后心功能障碍的关系。方法38只SPF级雄性SD大鼠按随机数字表法分为对照组（12只）......
用ＤＥＡＥ－Ｓｅｐｈａｃｅｌ层析法部分纯化了大鼠心肌肌浆网ｐｈｏｓｐｈｏｌａｍｈａｎ（ＰＬＢ）蛋白磷酸酶（ＰＰａｓｅ），并证明其是ＰＰａｓｅ－１。在ＳＤＳ－ＰＡＧＥ电泳放射自显影上证明，ＥＳ大鼠心肌ＳＲ部分纯化的ＰＬＢＰＰａｓｅ对底物（３２Ｐ－磷酸化酶ａ和３２Ｐ－ＳＲ）的去磷酸化......
Aim:The downregulation of phospholamban (PLB) and FKBPI 2.6 as a result of βreceptor activation is involved in the path......
,Construction of phospholamban antisense RNA recombinant adeno-associated virus vector and its effec
Aim: To construct a recombinant adeno-associated virus (rAAV) vector containing gene encoding phospholamban antisense RN......
,C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP
Phosphodiesterase-9A (PDE9A) expression is upregulated during cardiac hypertrophy and heart failure.Accumulating evidenc......
,Differential Iocalizations of protein phosphatase 1 isoforms determine their physiological function
Protein phosphatase 1 isoforms α,β,and 7 (PP1α,PP1β,and PP1γ) are highly homologous in the catalytic domains but ha......
Phospholamban Antisense RNA Improves SR Ca2+-ATPase Activity and Left Ventricular Function in STZ-in
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
有研究发现扩张型心肌病(DCM)不仅与环境因素有关,还有显著的遗传学基础.受磷蛋白(PLN)基因是其中的一种相关遗传基因,编码心肌收......
Phospholamban Antisense RNA Improves SR Ca2+-ATPase Activity and Left Ventricular Function in STZ-in
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目的研究扩张型心肌病(DCM)患者的肌浆网受磷蛋白(phospholamban, PLN)基因突变情况,探讨该基因与中国DCM患者发病的关系.方法采用......
用ＤＥＡＥ－Ｓｅｐｈａｃｅｌ层析法部分纯化了大鼠心肌肌浆网ｐｈｏｓｐｈｏｌａｍｂａｎ（ＰＬＢ）蛋白磷酸酶（ＰＰａｓｅ），并证明其是ＰＰａｓｅ－１。在ＳＤＳ－ＰＡＧＥ电泳放射自显影上证明，ＥＳ大鼠心肌ＳＲ部分纯化的ＰＬＢＰＰａｓｅ对底物＾３２Ｐ－磷酸化酶ａ和＾３２Ｐ－ＳＲ）的去磷酸化......
目的检测持续性心房颤动（简称房颤）患者心房肌中丝／苏氨酸蛋白磷酸酶的活性变化并探讨其意义。方法用荧光法检测16例持续性房颤及14例......
目的：观察糖尿病（DM）大鼠心肌磷酸受纳蛋白（PLB）基因表达和肌浆网Ca^2＋-ATPase活性的变化及其与心功能的关系。方法：复制糖尿病大鼠模型，分......
目的：探讨腺相关病毒载体介导的磷酸受纳蛋白（PLB）反义RNA对肌浆网Ca^2＋-ATPase活性以及细胞内钙浓度（[Ca^2＋]i）的作用。方法：构建PLB反义R......
Phospholamban Antisense RNA Improves SR Ca2＋-ATPase Activity and Left Ventricular Function in STZ-in
与糖尿病 mellitus (DM ) 在老鼠在 sarcoplasmic 蜂窝胃 Ca2+-ATPase 活动和心脏的功能学习 phospholamban antisense RNA (asPLB......
目的：探讨心力衰竭（心衰）心肌细胞磷酸化受磷蛋白表达异常的临床意义。方法：将20只家兔随机分为两组：假手术组和心衰组，各10只。通过超容......
目的对一个扩张刑心肌病（dilated cardiomyopathy，DCM）家系行候选致病基因全外显子高通量测霄，以寻找该家系的致病基因，并分析其基因型......
Endogenous modulators in the regulation of ion transporting enzymes: structure, function, interactio
A prerequisite for life is the ability to uphold electro-chemical imbalance across biomembranes. Ion trans- porting enzy......
目的过氧化氢过氧化物酶（peroxiredoxinⅡ，PrxⅡ）主要位于细胞的胞浆，可将体内多余的过氧化氢还原为水，PrxII属于过氧化氢过氧化物酶超......
Improved Solid-Phase Peptide Synthesis of Wild-Type and Phosphorylated Phospholamban Using a Pseudop
In this study, we report that the insertion of a pseudoproline dipeptide for the solid-phase peptide synthesis of wild-t......
Microwave Assisted Peptide Synthesis as a New Gold Standard in Solid Phase Peptide Synthesis: Phosph
In this study, we report the microwave assisted synthesis of Phospholamban protein (WT-PLB) as a new gold standard in so......
