allodynia相关论文
Involvement of microglia and interleukin-18 in the induction of long-term potentiation of spinal noc
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Proteomic Analysis of the Hippocampus in Mouse Models of Trigeminal Neuralgia and Inescapable Shock-
To investigate the behavioral and biomolecular similarity between neuralgia and depression,a trigeminal neuralgia (TN) m......
Objective Lipoxins represent a unique class of lipid mediators that can function as "braking signals" in inflammation.......
Magnesium L-threonate attenuate vincristine-induced mechanical allodynia and hyperalgesia via inhibi
Although vincristine is a frontline antineoplastic agent for treatment of tumors,the vincristine evoked pain syndrome is......
Neuroinflammation involving both astrocyte and microglia mediates mechanical allodynia induced by in
Objective Cancer pain, especially bone cancer pain, affects the life quality of cancer patients, and current treatments ......
Cannabinoid receptor-2 contribute to the regulation of electroacupuncture on expression of β-endorph
Objective It has been reported that EA-produced analgesia is mediated by endogenous opioid systems in uninjured and infl......
Fibromyalgia Syndrome (FMS) is a chronic condition of widespread musculoskeletal pain.It is clinically characterized by ......
Melzak and Wall(Science,1965)proposed a well-known hypothesis,the gate theory of pain,which is highly influential for ne......
Proteomic analysis of the hippocampus from trigeminal neuralgia and inescapable shock induced depres
To investigate the behavioral and biomolecular similarity between neuralgia and depression,a trigeminal neuralgia(TN)mou......
Blockade of persistent sodium currents contributes to the riluzole-induced inhibition of spontaneous
In addition to a fast activating and immediately inactivating inward sodium current, many types of excitable cells posse......
Using tail-flick latency as the nociceptive index and von Frey hair to measure the mechanical allodynia, the aim of the ......
目的：分析偏头痛患者皮肤异常性痛觉（CA）现象及其危险因素，观察普瑞巴林对CA的治疗效果。方法选择符合偏头痛诊断标准的63例患者，根据异......
,Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia a
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神经病理性疼痛程度重、治疗效果差,严重影响患者生活质量.神经病理性疼痛的病因有创伤、压迫、神经毒性药物、感染、自身免疫性疾......
目的 观察谷氨酸转运体GLAST在骨癌痛小鼠脊髓中表达的变化.方法 35只C3H/HeJ小鼠随机分为2组:骨癌痛组(Ca组,n=30)和假手术组(Sha......
目的 探讨三叉神经颈髓复合体内缝隙连接蛋白43(Cx43)对偏头痛大鼠痛觉超敏的影响. 方法 将SD大鼠随机数字表法分为空白组、假手术......
目的 研究大鼠面部慢性炎症痛与三叉神经节内表达P2X3受体亚型神经元细胞大小和表型变化之间的关系。方法 参照Neumann（1996）报道的......
目的：观察预防性腹腔给予己酮可可碱对大鼠腰5脊神经切断后机械痛觉过敏的作用，以及相应脊髓节段胶质细胞活化、炎症及细胞因子表达......
目的：探讨鞘内注射18 kDa转运蛋白（18 kDa translocator protein,TSPO）配体对神经病理性疼痛（neuropathic pain,NP）的调节作用及其可能......
目的观察Src-家族激酶(SFKs)的激活在外源性TNFα引起的机械痛敏中的作用。方法大鼠坐骨神经周围施加重组大鼠TNFα(rrTNF),免疫组......
目的 探索强啡肽（Dyn)A(1-13)及A（2－17）致大鼠异常性疼痛的作用及其受体机制。方法 ①鞘内注射非致瘫剂量DynA(1－13）及A(2-17)后检测发......
疼痛和另外的感觉症状的理解和描述在在有胃肠的混乱的病人的诊断和评价的最重要的问题之中。唤起并且估计试验性的疼痛的方法最近......
痛觉过敏一向被归咎于外周伤害性感受器的敏感化。新近有证据表明，中枢神经元的敏感化和高兴奋性在痛觉过敏的发生发展中具有至关重......
目的：脊椎间盘突出、椎间孔狭窄、脊髓损伤以及肿瘤造成的背根节（dorsal root ganglion，DRG）及其邻近神经根的机械性压迫可能是引起腰......
目的观察己酮可可碱腹腔注射对选择性坐骨神经分支损伤大鼠（SNI）脊髓星形胶质细胞的影响。方法切断腓总神经和胫神经保留腓肠神经，制......
Pain receptors, nociceptors inputs to the spinal cord and supra spinal structures triggering a prolonged but reversible ......
The development of chronic pain after amputations is not an uncommon event.In some cases the most disabling problem is r......
为研究脊髓水平环氧合酶（COX）-1在术后疼痛形成和维持中的作用，运用免疫组化和免疫蛋白印记法观察切口痛模型大鼠腰段脊髓中COX-1蛋自......
Our group has earlier demonstrated that three enzymes sensitive to peptidase inhibitors (PIs), amastatin (A)-, captopril......
Temporal and Qualitative Differences in the Development of Allodynic Behaviors between Mice and Rats
The spared nerve injury (SNI) model of neuropathic pain was first developed by Decosterd and Woolf in 2000 in Sprague Da......
