Ure2相关论文
Observation of conformational changes during amyloid fibril assembly of Ure2 by single-molecule tech
Ure2 is the protein determinant of the [URE3] prion state in Saccharomyces cerevisiae,and it forms amyloid fibrils in vi......
Uncovering amyloid formation mechanism of yeast prion Ure2 by single molecule FRET and kinetic analy
Protein aggregation to form amyloid fibrils is associated with a variety of neurodegenerative diseases,in which olig......
1.肌酸激酶折叠机制的进一步研究 研究了二体肌酸激酶被脲变性的平衡态和动力学去折叠/重折叠过程,确定并比较了平衡态和动力学折......
酵母Saccharomycescerevisiae体内的prion蛋白Ure2在体内和体外都会形成淀粉样纤维,其富含天冬酰胺和谷氨酰胺重复序列的N-端(1-89)......
Prion疾病的一个重要特征是由于蛋白质错误折叠而导致的淀粉样聚集,在对prion形成机制的探索中,蛋白质折叠与淀粉样纤维化关系的研究......
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包括亨廷顿疾病,阿尔茨海默氏病以及帕金森病在内的一系列神经退行性疾病都与相关蛋白在神经元中形成淀粉样纤维有着密切联系。相对......
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