SILDENAFIL相关论文
目的:观察机械通气联合不同剂量西地那非治疗新生儿持续性肺动脉高压（PPHN）的疗效及安全性。方法:选取2018年1月至2019年12月德州市......
Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal
Aim: To study the effects of homocysteine and copper on type 5 phosphodiesterase (PDE5) expression in cavernosal vascula......
Chronic administration of sildenafil improves erectile function in a rat model of chronic renal fail
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An analysis of treatment preferences and sexual quality of life outcomes in female partners of Chine
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Thecardiopulmonaryandtreatmenteffectofinhaledsolubleguanylatecyclaseactivatorforphosgene
目的 Toexplorethecardiopulmonaryandtreatmenteffectofsolubleguanylatecyclase(sGC)activatorforphosgene-inducedacutelunginj......
Purpose Whileamyloid-centeredetiologyremainstobetheleadinghypothesisinAlzheimersdisease(AD),experimentaltherapiestargeti......
Aim: Sildenafil, a phosphodiesterase type 5 inhibitor, has been found to produce functional recovery in ischemic rats by......
Purpose: Voltage-dependent potassium (Kv) channels in pulmonary artery smooth muscle cells (PASMCs) are thought to play ......
Effect of Icariin in combination with daily sildenafil on penile atrophy and erectile dysfunction in
Introduction:The commonly utilized phosphodiesterase type 5(PDE5)inhibitors does not lead to satisfactory penile erectio......
Systematic review and meta-analysis of phosphodiesterase type 5 inhibitors for the treatment of fema
Objective: To obtain systematic and comprehensive evidence regarding the benefits and safety of PDE5i compared to those ......
Sildenafil,phosphodiesterase V inhibitors attenuate LPS-induced pro-inflammatory responses through d
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Assisted semen collection using two phosphodiesterase type 5 inhibitors (Tadalafil and Sildenafil) i
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The safety,efficacy and pharmaceutical quality of male enhancement nutraceuticals bought online:Trut
Objective:Nutraceutical products are widely used for their claimed therapeutic benefits.However,falsified or adulterated......
目的探讨西地那非对系统性红斑狼疮合并肺动脉高压患者的临床疗效及对血清辅助性T细胞17(Th17)、血小板反应蛋白1(TSP-1)水平的影......
目的 明确维持性血液透析（MHD）男性患者勃起障碍的发病率，及评价西地那非的疗效与副作用。方法 以国际勃起功能指数（IIEF）对22例HD男患......
目的：探讨灌胃不同剂量枸橼酸西地那非（sildenafil ciltrate,Sn；商品名Viagra）后对大鼠性行为的影响，为ED药物治疗后性行为的变化提供动......
目的 观察西地那非对肺动脉高压(PH)的临床治疗效果,为PH的临床治疗提供更多的理论依据.方法 选择80例PH患者,按随机数字表法分为......
西地那非(sildenafil)用于治疗男性勃起功能障碍的一线药,具有里程碑意义.近些年相关研究已证实西地那非通过选择性抑制5型磷酸二......
目的探讨西地那非和高频振荡通气(HFO)治疗新生儿呼吸衰竭并肺动脉高压的疗效。方法选择2012年12月至2015年1月我院NICU收治的急性......
目的:检测100批缓解体力疲劳类保健食品中违法添加西地那非、他达拉非、伐地那非、红地那非、豪莫西地那非、羟基豪莫西地那非、那......
目的 探讨西地那非导致肝损伤的临床表现及处理措施.方法 通过对1例男性患者应用西地那非致肝内胆汁淤积的案例报道,并结合相关文......
Determination of sildenafil by preconcentration on surfactant coated polymeric resin followed by spe
The illicit addition of phosphodiesterase type-5(PDE-5) inhibitors like sildenafil(Viagra) in product offered as herbal ......
目的 分析按需口服西地那非治疗勃起功能障碍(ED)无效原因并制定治疗策略.方法 2009年1-12月因ED就诊、正确服用西地那非100 mg、......
目的:探讨西地那非治疗新生儿持续肺动脉高压(PPHN)的疗效与安全性。方法:将60例肺源性PPHN患儿随机分成硫酸镁组、米力农组、西地......
目的:探讨枸橼酸西地那非治疗酒精依赖勃起功能障碍的临床疗效以及对患者生活质量的影响。方法:采用自身对照、运用One-way ANOVA......
目的探讨高脂饮食及CYP3A4*1G(rs2242480)基因多态性对西地那非中国健康人体药动学的影响。方法 32例健康男性受试者分别接受空腹......
功能性单心室患者Fontan手术成功的关键主要取决于肺血管阻力.Fontan循环中高肺血管阻力将带来各种并发症,如运动耐量下降、低心排......
cGMP-PDE5抑制剂抑制剂Silenafil是临床上第一个专门的有效治疗ED的口服药,由美国Pfizer公司研究开发.Sildenafil,化学名为5-[2-乙......
,Sildenafil and FDP-Sr attenuate diabetic cardiomyopathy by suppressing abnormal expression of myoca
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,Sildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine h
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目的 探讨西地那非对高原人体耐缺氧抗疲劳有关生化指标的影响. 方法 在海拔3700 m选择10名已习服半年的男性士兵,在海拔5380 m选......
Sildenafil potentiates the proliferative effect of porcine pulmonary artery smooth muscle cells indu
Background Sildenafil is one of the selective phosphodiesterase 5 inhibitors that has been proven by many investigators ......
Assisted semen collection using two phosphodiesterase type 5 inhibitors (Tadalafil and Sildenafil) i
In the past 50 years,dramatic advances have been achieved in male infertility treatment.Intracytoplasmic sperm injection......
目的通过分析室颤猪模型复苏前后血流动力学变化与心肌组织液中儿茶酚胺与乳酸水平的变化，研究西地那非预处理对复苏后心功能的保护......
新生儿持续性肺动脉高压(persistent pulmonary hypertension of the newborn,PPHN)又称持续胎儿循环(persistent fetalcirculatio......
Rapid Detection of Sildenafil Drugs in Liquid Nutraceuticals Based on Surface-Enhanced Raman Spectro
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的:观察西地那非对西藏小型猪慢性肺动脉高压(PH)模型体循环压力的影响。方法:18头2月龄西藏小型猪随机分为正常对照组、模型组......
【摘要】西地那非是一种具有高度选择性的磷酸二酯酶抑制剂,通过抑制第二信使cGMP的代谢,发挥其治疗作用。研究表明西地那非口服对......
目的 探讨西地那非治疗新生儿持续肺动脉高压的疗效与安全性.方法 .2005年1月至2008年10月本院新生儿重症监护室收治的持续肺动脉......
目的评价西地那非在干预男性肾移植受者手术前后勃起功能时的有效性及安全性。方法选取年龄23～58岁、移植肾存活1年以上、血肌酐在......
目的 探讨西地那非治疗新生儿持续肺动脉高压的疗效与安全性.方法 2005年1月至2008年10月收治持续肺动脉高压患儿45例,其中男25例,......
目的:探讨前列腺癌根治术(RP)后发生的勃起功能障碍(ED)应用负压勃起装置(VED)治疗的疗效和安全性.方法:2009年3月至2012年12月就......
A novel series of pyrido[1,2-e]purin-4(3H)-one derivatives containing polar substituents on 5-position were designed and......
目的 观察高肺血流肺动脉高压大鼠肺血管结构重建和肺血管电压依从钾通道Kv1.5mRNA表达变化,探讨口服西地那非对高肺血流肺动脉高......
目的：研究西地那非联合视听性刺激诱发心理性ED患者勃起后的阴茎血流动力学参数变化。方法选择心理性ED患者20名，口服枸橼酸西地那非......
目的 国外研究表明西地那非能有效地降低肺动脉高压,改善活动耐量,提高生活质量.但中国肺动脉高压患者服用西地那非的效果和安全性......
AIM: To investigate if sildenafil increases splanchnic blood flow and changes the hepatic venous pressure gradient (HVPG......
