CALMODULIN相关论文
Up-regulation of calmodulin involved in the stress response to cyantraniliprole in the whitefly,Bemi
Cyantraniliprole is the first diamide insecticide to have cross-spectrum activ-ity against a broad range of insect order......
Identification of a novel testis-specific gene and its potential roles in testis development/spermat
Aim: To identify and characterize a novel gene with potential roles in testis development and spermatogenesis.Methods: A......
Alm: To analyze both the expression and distribution of the voltage-gated sodium channels (VGSCs) subtypes-Nav1.1, Nav1.......
Direct inhibition of calmodulin inhibitor,CGS 9343B on voltage-dependent K+Channels expressed in art
We investigated the effects of the calmodulin inhibitor CGS 9343B on voltage-dependent K+(Kv)channels using whole-cell p......
Calmodulin(CaM),a multifunctional Ca2+sensor,mediates multiple reactions involved in plant growth and environmental stre......
Low Mg2+ treatment increases the sensitivity of voltage-gated sodium channels to the Ca2+/calmodulin
The purpose of this study was to investigate the effect of Ca2+/calmodulin (CaM) on voltage-gated sodium channels (VGSCs......
Modulation of calmodulin on persistent Na + current in Mg2+-free induced epileptiform discharge mode
OBJECTIVE A slowly persistent Na + current (INaP) has been found in neurons and the abnormal change of in INaP has been ......
Background: The binding free energy is the most important physical parameter that reveals the binding affinity of the re......
Function of Ca2+-/calmodulin-dependent protein kinase Ⅳ in Ca2+-stimulated neuronal signaling and be
The activity of Ca2+/calmodulin-dependent protein kinase Ⅳ (CaMKIV) is sensitive to activity-dependent changes in the l......
Calmodulin-and Ca2+-dependent facilitation and inactivation of the CaV1.2 Ca2+ channels in guinea-pi
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24.ALTERATIONS IN CALCIUM HOMEOSTASIS ON FLUORIDE EXPOSURE IN RAT BRAIN SYNAPTOSOMES AND AMELIORATIO
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In the present study,the roles of Ca2+/CaM dependent protein kinase Ⅱ (CaMKⅡ) and Calf Intestinal Alkaline Phospha......
CalciumCalmodulin-dependent Protein Kinase Ⅱ Inhibition Induces Hyperexcitability by Abnormal Intera
Abnormal calcium/calmodulin (CaM)-dependent kinase Ⅱ (CaMKⅡ) changes have been shown to be involved in many epilep......
CalciumCalmodulin-dependent Protein Kinase Ⅱ Inhibition Induces Neuronal Death in a Rat Model of Gen
Abnormal Calcium/calmodulin (CaM)-dependent kinase Ⅱ (CaMKⅡ) change has been involved in many epileptic models.......
Neuropeptide Y exerts neuroprotective function to an animal model of genetic epilepsy Tremor rat ass
Neuropeptide Y (NPY) is an endogenous neuropeptide which is recognized as an important modulator of classical neurot......
Allosteric regulation and cooperativity are essential molecular features of cellular signaling and regulation, allowing ......
Many of the effects of Ca2+ signaling are mediated through the Ca2+/calmodulin complex and its acceptors, the Ca2+/calmo......
THE CHANGE OF CALMODULIN LEVEL AND ITS RELATIONS WITH THE FLOWERING AND SENESCENCE IN Lemna perpusil
Since the finding of CaM, i. e. Ca<sup>2+</sup>-receptor in animals and plants, the roles of Ca<sup>2+</sup> and CaM act......
calmoddin (凸轮) 的效果花粉萌芽和试管生长 ofForsythia suspensu 上的对手 W7-agarose，反凸轮浆液和外长的净化的凸轮被学习。花......
利用碘乙酰胺氮氧自由基标记钙调蛋白研究了它与三氟拉嗪（ＴＦＰ）、酸枣仁皂甙Ａ（ＪｕＡ）的相互作用。结果表明，每分子ＣａＭ分别至少可以结合两分子的ＴＦＰ及ＪｕＡ，它们......
外源钙调蛋白（ＣａＭ）对胡萝卜悬浮细胞增殖具明显促进作用，不同浓度ＣａＭ的促进程度不同，７μｇ／ｍｌ时促进作用最大。ＣａＭ抑制剂ＴＦＰ则明显抑制该悬浮细胞的增殖，ＴＦＰ浓......
采用固相法设计合成了４个蜂毒肽片段，Ｍｅｌ １２，Ｍｅｌ １３，Ｍｅｌ １４，Ｍｅｌ １５。应用电泳技术，抑制钙依赖性的磷赖性的磷酸二酯酶酶活方法和荧光技术研究了这些多肽与......
本文报导了一种能同时纯化钙调神经磷酸酶和钙调素的有效方法。牛脑粗提液经DE-52纤维素层析分段洗脱:0.5mol/L NaCl缓冲液洗脱峰......
钙调素作为Ｃａ＾２＋信号的主要胞内受体，在细胞增殖调节中起着重要作用，实验中运用ＤＮＡ体外重组技术构建了高表达钙调素的真核载体，并将其转染到大......
X-band electron spin resonance spectroscopy was used to investigate the binding of Mn<sup>2+</sup>tothe apo-forms of cal......
Calmodulin (CaM) is a multifunctional Ca2+-binding protein regulating the activity of many enzymes in response to fluctu......
钙调素(calmodulin,CaM)是一种真核细胞内的多功能调节蛋白,对免疫功能有调控作用。慢性淋巴细胞性甲状腺炎又称桥本病(HT),和甲亢......
The roles and relations of calpastatin,calmodulin and an undefined cytoplasmic factor in the regulat
Objective To explore the mechanism that cytoplasmic factors could recover L-type Ca2+ channel activity after “run-down......
目前有关氟中毒作用机制尚不完全清楚,其和许多因素都有关系。有学者显示氟中毒是“钙矛盾疾病”,和钙营养失调有关。细胞的各种生......
目的观察碘缺乏和甲状腺功能减退对大鼠仔鼠海马钙调蛋白(calmodulin)表达的影响。方法健康2月龄雌性Wistar大鼠,交配妊娠后,取孕......
考察角鲨烯对慢性轻度不可预见刺激模型小鼠行为学及其谷氨酸毒性通路相关蛋白的影响。采用13种不同刺激[食物剥夺、噪音、闪光、......
钙调神经磷酸酶（calcineurin，CaN），是迄今所知的惟一一种受Ca^2＋／钙调蛋白（calmodulin，CaM）调节的丝氨酸／苏氨酸蛋白磷酸酶。CaN广泛分布于机......
CaMKⅡ是钙/钙调蛋白激酶(Ca2+/calmodulin-dependent protein kinase,CaMK)成员之一。心脏中的CaMK包括Ⅰ,Ⅱ和Ⅳ三种类型,CaMKⅡ......
Molecular mechanisms and therapeutic perspectives of left ventricular hypertrophy in systemic hypert
Background Left ventricular hypertrophy(LVH) induced by systemic hypertension represents a maladaptive response to the i......
AIM: Programmed necrosis( necroptosis) and apoptosis are crucially involved in multiple severe cardiac pathological cond......
Calcineurin (CN) is the only protein phosphatase known to be under the control of calcium (Ca2+) and calmodulin (CaM). ......
AIM:Many growth factors,such as epidermal growth factor(EGF),are associated with the carcinogenesis.EGF plays itsrole i......
Effect of O-4-ethoxyl-butyl-berbamine in combination with pegylated liposomal doxorubicin on advance
AIM:To study the synergistic effects of calmodulin (CaM)antagonist O-4-ethoxyl-butyl-berbamine (EBB) and pegylatedlipos......
目的 构建钙调蛋白(CaM)N2和C2突变体的表达性载体,表达纯化并进行活性鉴定,为进一步研究CaM与钙通道片段的相互作用奠定基础.方法......
The Role of Extracellular Ca2+Influx, Intracellular Ca2+ Release and Calmodulin in Mouse Egg Fertili
The effects of various Ca2+-modifying drugs on moue egg fertilization were studied. Ca2+ chelator,rnethylen glycol-bis-(......
目的 观察刨伤性脑损伤(traumatic brain injury,TBI)大鼠脑组织匀浆及线粒体Na+-K+-ATP酶、Ca2+-ATP酶活性、神经细胞内游离Ca2+......
The effects of alveolar macrophage (Amφ) conditioned media from interstitial lung disease (ILD) patients on fibroblast ......
In the present study, the role of calcium in endotoxin-induced CGRP release was studied. 2 .5-50 μg/mL endotoxin and 1......
Brain ischemia induces serine phosphorylation of neuronal nitric oxide synthase by Ca~(2+)/calmoduli
AIM: To investigate whether brain ischemia induces serine phosphorylation of neuronal nitric oxide synthase(nNOS) by Ca2......
