Alzh相关论文
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Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide
Amyloid-beta peptide is the main component of amyloid plaques, which are found in Alzhei-mer’s disease. The generation ......
There are several major pathological changes in Alzheimer’s disease, including apoptosis of cho-linergic neurons, overa......
目的探讨人Neprilysin基因在小鼠MSCs中的表达情况。方法分离培养小鼠MSCs，采用分子克隆技术构建Neprilysin—pEGFP重组质粒，将此Nep......
老年性痴呆又称为阿尔茨海默病(Alzheimer Disease,AD),归属于中医“痴呆病”范畴。本文通过从八纲辨证的角度分析老年性痴呆的本......
植物雌激素是一类在很多中药中也广泛存在的，具有类似雌激素生物活性的植物成分。近年来，更多的研究表明植物雌激素可能在预防和治疗......
目的研究丝裂原活化蛋白激酶磷酸酶-1（MKP-1）在APP/PS1双转基因小鼠脑中的分布和表达,探索MKP-1与阿尔茨海默病（AD）的关系。方法选取3......
目的构建并纯化含有柔性肽串联四价β-淀粉样蛋白（Aβ15）的重组腺病毒疫苗,用于老年性痴呆的预防和治疗。方法酶切获取带有IgGк轻链......
他汀类药物已在临床广泛使用,除降血脂作用外,其对痴呆的防治作用正逐渐引起人们的关注.在中年人中高胆固醇血症可能与痴呆呈正相......
目的:探讨大豆异黄酮活性组分对H2O2诱导的PC12细胞损伤的保护作用.方法:以H2O2损伤PC12细胞为氧化应激损伤的模型,采用光学显微镜......
目的探讨DR4的激活对海马神经元树突棘形态学的影响,进而探讨阿尔茨海默病的发病机制及治疗新方法。方法30只Wistar雄性大鼠随机分......
环氧合酶（COX）是非甾体抗炎药的主要作用靶点。自从上世纪90年代初被发现至今，COX已被证实广泛参与炎性反应过程。小胶质细胞是介导“......
Gengnianchun recipe inhibits apoptosis of pheochromocytoma cells from beta-amyloid 25-35 insult, bet
This study aims to determine and compare the protective effects of Gengnianchun recipe drug serum and compounds of its r......
目的 观察电针合并奋乃静治疗ＡＤ的疗效。方法 随机分两组，治疗组１６例，采用电针加奋乃静，对照组１４例，单纯用奋乃静。结果 两组疗效相似。结......
OBJECTIVE The aim of the present study was to investigate the effect of cornel iridoid glycoside(CIG)on tau hyperphospho......
Association between Caregiver Quality of Life and the Care Provided to Persons with Alzheimer’s Dise
We reviewed the literature to examine whether an association exists between the quality of life (QoL) of primary informa......
