固有免疫主要由吞噬细胞和免疫分子组成,在机体抵御感染中具有重要作用。任一组成成份的缺陷,均可导致机体对病原体的易感性。近年来,越来越多的固有免疫缺陷病被报道,为促进对该类疾病的认识,本文就此做一综述。 Innate immunity is mainly composed of phagocytes and immune molecules, plays an important role in the body against infection. Any one of the components of the defect, can lead to the body’s susceptibility to pathogens. In recent years, more and more cases of innate immune deficiency disease have been reported. In order to promote the understanding of these diseases, this article reviews this issue.