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大剂量静脉注射甲基强地松龙的“冲击”疗法已成功地用于预防急性肾移植排斥,对严重的肾小球肾炎及增生性狼疮肾炎也都有效.作者们用此方法治疗2例危重的无肾脏损害的红斑性狼疮获得意外良效.方法是每日静脉注射甲基强地松龙1克,连续用药3~5日,待危急症状消退、化验指标好转后即可停用“冲击”疗法,改为口服皮质类固醇等常规治疗.
High-dose intravenous injection of methylprednisolone “shock” therapy has been successfully used to prevent acute renal transplant rejection, severe glomerulonephritis and proliferative lupus nephritis are also effective. The authors treated with this method 2 cases of severe lupus erythematosus without renal damage obtained accidental good effect.Method is daily intravenous injection of 1 g of methylprednisolone, continuous medication 3 to 5, until the critical symptoms subsided, the test index can be stopped after the improvement With “shock” therapy, to oral corticosteroids and other conventional treatment.