目的:探讨米索前列醇在绝经后取环中的应用方法及效果。方法:搜集2014年6月-2015年6月我院接收的绝经取环手术65例妇女,按照有无在取环手术前口服米索前列醇分为对照组与实验组。给予对照组32例在取环手术前不服用米索前列醇,给予实验组33例围在取环手术前服用米索前列醇。观察并对比对照组与实验组的手术效果。结果:实验组妇女在取环过程中宫颈软化程度高,疼痛感较轻,取环效果好于对照组有明显差异,有统计学意义(P<0.05)。结论:在妇女绝经后取环术前服用米索前列醇,能有效提高宫颈然后成功,减轻疼痛感,提高取环效果,满意度较高,值得推广。 Objective: To explore the application of misoprostol in postmenopausal ring and its effect. Methods: A total of 65 women undergoing menopause operation in our hospital from June 2014 to June 2015 were divided into control group and experimental group according to the presence or absence of oral misoprostol. 32 cases in the control group were given no misoprostol before taking the ring and 33 cases in the experimental group were given misoprostol before taking the ring. Observed and compared the control group and experimental group surgical results. Results: In the experimental group, the degree of cervix softening in the experimental group was high, the pain was mild, and the effect of taking the ring was better than that of the control group (P <0.05). Conclusion: Taking misoprostol before taking preoperative menopause in women can effectively improve the success of the cervix, relieve the pain and improve the effect of taking the ring. It is worthy of promotion.