小儿治哮方联合酮替芬治疗儿童咳嗽变异型哮喘临床研究

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目的:观察小儿治哮方联合酮替芬治疗儿童咳嗽变异型哮喘的疗效。方法:选取在本院治疗的120例咳嗽变异型哮喘患儿作为研究对象,随机分为实验组和对照组各60例,实验组采用小儿治哮方联合酮替芬进行治疗,对照组采用丙卡特罗联合酮替芬进行治疗,2组均以服药2周为1疗程,1疗程结束后评价治疗效果。随访3月。比较2组患儿的治疗效果。结果:服药1疗程后,总有效率实验组为98.33%,对照组为76.67%,2组比较,差异有非常显著性意义(P<0.01)。治愈率实验组为100%,对照组为88.33%,2组比较,差异有非常显著性意义(P<0.01)。实验组患儿复发率(5.00%)低于对照组(32.08%),差异有非常显著性意义(P<0.01)。对照组不良反应发生率高于实验组,差异有显著性意义(P<0.05)。结论:采用小儿治哮方联合酮替芬治疗咳嗽变异型哮喘患儿疗效肯定,安全可靠。 Objective: To observe the curative effect of pediatric treating asthma combined with ketotifen on cough variant asthma in children. Methods: A total of 120 children with cough variant asthma treated in our hospital were selected as study subjects and randomly divided into experimental group and control group with 60 cases each. The experimental group was treated with pediatric treatment of asthma combined with ketotifen and the control group with C In combination with ketotifen and ketotifen, both groups were given 1 course of treatment for 2 weeks and evaluated after 1 course of treatment. Followed by March. The therapeutic effects of two groups were compared. Results: After taking a course of treatment, the total effective rate was 98.33% in the experimental group and 76.67% in the control group. There was significant difference between the two groups (P <0.01). The cure rate was 100% in the experimental group and 88.33% in the control group. There was significant difference between the two groups (P <0.01). The recurrence rate in experimental group (5.00%) was lower than that in control group (32.08%), the difference was significant (P <0.01). The incidence of adverse reactions in the control group was higher than that in the experimental group, the difference was significant (P <0.05). Conclusion: Pediatric treatment of asthma combined with ketotifen treatment of children with cough variant asthma affirmed, safe and reliable.
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