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作者对246例各类关节炎病人和50例健康人的血清,用间接免疫荧光法,测定其抗类风湿性关节炎协同核抗原抗体(Antibody against rheumatoidarthritis-associated nuclear antigen,抗RANA抗体)。发现类风湿性关节炎组病人,血清中抗RANA抗体存在的机率明显高于其它组:103例类风湿因子阳性的病人中存在抗RANA抗体者有96例(93%),21例类风湿因子阴性的病人中有20例(95%);而122例其它各类型关节炎的患者平均只有19%有抗RANA抗体,对照组的50例健康人只有16%。抗RANA抗体的存在与疾病的活动性、病程、抗类风湿
The author of 246 cases of various types of arthritis patients and 50 healthy people serum, indirect immunofluorescence assay for anti-rheumatoid arthritis with nuclear antigen antibody (Antibody against rheumatoid arthritis-associated nuclear antigen, anti-RANA antibody). Found that patients with rheumatoid arthritis, the serum anti-RANA antibody was significantly higher than the other groups: 103 cases of rheumatoid factor-positive patients with anti-RANA antibody were 96 cases (93%), 21 cases of rheumatoid factor Negative patients were 20 (95%); while in 122 other types of arthritis, only an average of 19% of patients with anti-RANA antibody, control group of 50 healthy people only 16%. Anti-RANA antibody presence and disease activity, duration, anti-rheumatoid