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目的:探讨肺心胶囊对慢性肺源性心脏病(CPHD)患者的治疗效果及作用机理。方法:将60例患者随机分为两组,对照组给予西医常规治疗,治疗组在西医常规治疗基础上以口服肺心胶囊治疗,2个月后,测定患者血中一氧化氮(NO)、内皮素-1(ET-1)的含量。结果:经治疗后,肺心胶囊可显著提高患者血中NO的含量、降低ET-1的含量(P<0.01或P<0.05)。结论:肺心胶囊对CPHD患者有较好的治疗效果,值得临床推广。
Objective: To investigate the therapeutic effect and mechanism of Feixin Capsule on patients with chronic cor pulmonale (CPHD). Methods: Sixty patients were randomly divided into two groups. The control group was treated with conventional Western medicine. The treatment group was treated by oral administration of Feixin Capsule on the basis of western medicine routine treatment. After two months, the levels of blood nitric oxide (NO) Endothelin-1 (ET-1) content. Results: After treatment, Feixin Capsule can significantly increase the content of NO in blood and decrease the content of ET-1 (P <0.01 or P <0.05). Conclusion: Feixin capsule has a good therapeutic effect on patients with CPHD and is worthy of clinical promotion.