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目的 观察α - 2b干扰素治疗慢性乙型肝炎近、远期疗效。方法 采用α - 2b干扰素治疗慢性乙型肝炎 ,并与同期使用胸腺肽组作对照观察。结果 应用α - 2b干扰素治疗 3个月、6个月治疗后、1a时其HBeAg转阴率分别为 33.33%、6 0 .6 1%、48.48% ;HBVDNA转阴率分别为 2 7.2 7%、5 7.5 8%、45 .45 %。结论 α- 2b干扰素治疗慢性乙型肝炎近、远期均显示了较好疗效 ,且疗效与疗程呈正相关。
Objective To observe the short-term and long-term therapeutic effects of interferon α-2b on chronic hepatitis B patients. Methods α - 2b interferon was used in the treatment of chronic hepatitis B, and compared with thymosin group for the same period. Results The α - 2b interferon treatment for 3 months, 6 months after treatment, 1a hour HBeAg negative rates were 33.33%, 60.1%, 48.48%; HBVDNA negative rates were 2 7.2 7% , 5 7.5 8%, 45.45%. Conclusion α-2b interferon treatment of chronic hepatitis B, long-term and long-term have shown a good effect, and the efficacy and course of treatment was positively correlated.