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目的探讨联合检测降钙素原(PCT)与C反应蛋白(CRP)在诊断呼吸道感染疾病中的应用价值。方法选取2016年1—6月大连市第二人民医院收治的180例呼吸道感染患者作为研究对象,通过血常规和细菌培养等检测方法将其分为细菌感染组与病毒感染组,各90例。另选取90例健康体检者为对照组。分别检测3组受试对象血清PCT、CRP水平。结果细菌感染组患者PCT、CRP水平均明显高于对照组,差异均有统计学意义(均P<0.05),细菌感染组与病毒感染组患者CRP水平差异无统计学意义(P>0.05);病毒感染组CRP水平明显高于对照组,差异有统计学意义(P<0.05),PCT水平与对照组比较差异无统计学意义(P>0.05);细菌感染组PCT和CRP的阳性率均明显高于对照组,异均有统计学意义(均P<0.05);细菌感染组PCT的阳性率明显高于病毒感染组,差异有统计学意义(P<0.05),CRP阳性率与病毒感染组差异无统计学意义(P>0.05);病毒感染组CRP阳性率明显高于对照组,差异有统计学意义(P<0.05),PCT阳性率与对照组比较差异无统计学意义(P>0.05)。结论 PCT和CRP的联合检测对于呼吸道感染性疾病中细菌性感染和病毒性感染的鉴别诊断具有重要意义。
Objective To explore the value of combined detection of procalcitonin (PCT) and C-reactive protein (CRP) in the diagnosis of respiratory tract infections. Methods A total of 180 patients with respiratory tract infection admitted to the Second People’s Hospital of Dalian from January to June 2016 were selected as subjects and divided into bacterial infection group and virus infection group by blood routine examination and bacterial culture test. Another 90 healthy people as the control group. The levels of serum PCT and CRP in three groups were detected respectively. Results The levels of PCT and CRP in bacterial infection group were significantly higher than those in control group (all P <0.05). There was no significant difference in CRP level between bacterial infection group and virus infection group (P> 0.05). The level of CRP in the virus-infected group was significantly higher than that in the control group (P <0.05). The PCT level was not significantly different from the control group (P> 0.05). The positive rates of PCT and CRP in the bacterial infection group were significantly higher (P <0.05). The positive rate of PCT in bacterial infection group was significantly higher than that in virus infection group, the difference was statistically significant (P <0.05). The positive rate of CRP was higher than that of virus infection group (P> 0.05). The positive rate of CRP in virus infection group was significantly higher than that in control group (P <0.05), while the positive rate of PCT was not significantly different from that in control group (P> 0.05 ). Conclusion The combined detection of PCT and CRP is of great significance for the differential diagnosis of bacterial infections and viral infections in respiratory infectious diseases.