1993年10月9日-11月7日某院婴儿室内发生一次新生儿肠道病毒感染,发病共22例,平均日龄7.5天,临床主要症状为发热(100%),心率增快(77.2%),气促(63.6%),黄疸(63.6%).周围血白细胞增高、血肠道病毒聚合酶链检测(PCR)19例,14例阳性,血柯萨基B_2病毒中和抗体滴度4倍以上上升.22例全部痊愈.经严格消毒隔离,加强管理制度,有效药物治疗,流行终止. From October 9 to November 7, 1993, there was a neonatal enterovirus infection in a hospital infantile. A total of 22 patients were diagnosed as having an average age of 7.5 days. The main clinical symptoms were fever (100%) and heart rate (77.2 %), Shortness of breath (63.6%), jaundice (63.6%), peripheral blood leukocytes increased, 19 cases of blood-borne virus polymerase chain reaction (PCR), 14 cases of positive, 4 times more than the rise of 22 cases were fully cured by strict disinfection and isolation, strengthening management system, effective drug treatment, epidemic termination.