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目的观察甲氨蝶呤联合米非司酮治疗异位妊娠患者的临床效果。方法将84例异位妊娠患者按照随机、自愿的原则分为对照组和观察组各42例。对照组给予甲氨蝶呤治疗,观察组给予甲氨蝶呤联合米非司酮治疗,疗程均为2周。比较2组患者治疗后血β-h CG恢复正常时间、包块消失时间和临床效果。结果观察组患者总有效率92.9%明显高于对照组71.4%,差异有统计学意义(P<0.05)。观察组患者血清β-h CG恢复正常时间和包块消失时间据明显小于对照组患者,差异均有统计学意义(P<0.05)。结论甲氨蝶呤联合米非司酮治疗异位妊娠患者的临床效果显著,可以有效加快患者康复,值得在临床推广应用。
Objective To observe the clinical effect of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods Eighty-four patients with ectopic pregnancy were divided into control group and observation group according to random and voluntary principles. The control group was treated with methotrexate, the observation group was given methotrexate combined with mifepristone treatment, the course of treatment was 2 weeks. Blood β-h CG recovery time, mass disappearance time and clinical effect were compared between the two groups. Results The total effective rate in observation group was 92.9%, which was significantly higher than that in control group (71.4%, P <0.05). The observation group patients serum β-h CG recovery time and mass disappeared significantly less than the control group patients, the difference was statistically significant (P <0.05). Conclusion Methotrexate combined with mifepristone in the treatment of ectopic pregnancy patients with significant clinical results, can effectively speed up the rehabilitation of patients, it is worth in the clinical application.