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顽固性蛋白尿的治疗至今仍是临床上的一个难题,近2年来我们用大剂量肌苷静滴治疗10例,收到了满意疗效,总结如下。 临床资料 一、一般资料 本组10例中男7例,女3例,年龄14～50岁,平均21.4岁。该组患者按1985年南京肾脏病会议分型:肾病综合征7例,慢性肾炎(普通型)2例,尿毒症1例。病程1周～5年,全部病例用药前均经过4～6周或以上的强的松(40～60mg/天Qd)或加用细胞毒药物(环磷酰胺0.2Qd)治疗而无效。
Stubborn proteinuria treatment is still a clinical problem, the past two years, we use high-dose intravenous infusion of inosine 10 cases, received a satisfactory effect, summarized as follows. Clinical data First, the general information The group of 10 patients, 7 males and 3 females, aged 14 to 50 years, an average of 21.4 years old. The group according to the 1985 Nanjing Nephropathy Conference classification: nephrotic syndrome in 7 cases, 2 cases of chronic nephritis (common type), uremia in 1 case. Duration of 1 week ~ 5 years, all patients before treatment after 4 to 6 weeks or more of prednisone (40 ~ 60mg / day Qd) or add cytotoxic drugs (cyclophosphamide 0.2Qd) treatment is ineffective.