论文部分内容阅读
氟卡胺(f1ecainide,又名哌氟酰胺)已广泛用于治疗成人室上性和室性心动过速,其副作用的发生率很低,尤其应用于抗室上性心律失常而患者心肌功能良好者。作者用氟卡胺治疗16例儿科和年轻成人室上性心动过速(SVT),对其临床效果、副作用和药代动力学进行了评估。患者和方法年龄为1个月～32岁(平均13岁),治疗前全都进行了侵入性电生理研究,采集完整病史,体格检查、行ECG、M型和二维超声心动图、胸部X线检查及24小时动态ECG监测。在连续遥测和不卧床监测的住院期间,开始氟卡胺治疗,3～4天后重
Flecainide (also known as flufenamide) has been widely used to treat adult supraventricular and ventricular tachycardia, the incidence of side effects is very low, especially for anti-ventricular arrhythmias and myocardial function in patients with good . The authors used flecainide in 16 pediatric and young adult patients with supraventricular tachycardia (SVT) and evaluated their clinical outcomes, side effects, and pharmacokinetics. Patients and methods ranged in age from 1 month to 32 years (mean, 13 years). All patients underwent invasive electrophysiological studies prior to treatment. Complete medical history, physical examination, ECG, M-mode and two-dimensional echocardiography, chest X-ray Check and 24-hour dynamic ECG monitoring. During the hospitalization of continuous telemetry and ambulatory monitoring, flucarbamy treatment was started, and after 3 to 4 days