【摘 要】
：
合成了两个新型不对称三齿多吡啶配体 ,3 ( 1,10 菲咯啉基 2 ) 1,2 ,4 三唑 (PHT) ,3 ( 1,10 菲咯啉基 2 ) 5 甲基 1,2 ,4 三唑 (PHMT) ,及其混配配合物 [Ru(tpy)
【机 构】
：
广西中医学院药学院 南宁530001
论文部分内容阅读
合成了两个新型不对称三齿多吡啶配体 ,3 ( 1,10 菲咯啉基 2 ) 1,2 ,4 三唑 (PHT) ,3 ( 1,10 菲咯啉基 2 ) 5 甲基 1,2 ,4 三唑 (PHMT) ,及其混配配合物 [Ru(tpy) (PHT) ] 2 + (Ru1)和 [Ru(tpy) (PHMT) ] 2 + (Ru2 ) ,通过元素分析、FAB MS ,ES MS ,1HNMR ,IR ,UV vis ,发射光谱和电化学对它们进行了表征 .运用电子吸收光谱、竞争性结合实验和粘度测试等方法研究了配合物与DNA的作用机理 ,结果显示它们均是通过静电作用与DNA结合 ,且Ru2与DNA的作用比Ru1与DNA的作用更强 .
Two novel asymmetric tridentate polypyridyl ligands, 3 (1,10-phenanthrolinyl 2) 1,2,4 triazole (PHT), 3 (1,10-phenanthrolinyl 2) 1,2,4-triazole (PHMT) and their complexes [Ru (tpy) (PHT)] 2 + (Ru1) and [Ru (tpy) (PHMT)] 2 + , FAB MS, ES MS, 1HNMR, IR, UV vis, emission spectroscopy and electrochemistry.The mechanism of interaction between DNA and the complex was studied by electron absorption spectroscopy, competitive binding assay and viscosity measurement. The results It is shown that both of them bind to DNA through electrostatic interaction, and the effect of Ru2 and DNA is stronger than that of Ru1 and DNA.
其他文献
A mangiferin aglycon derivative J99745 has been identified as a potent xanthine oxidase (XOD) inhibitor by previous in vitro study.This study aimed to evaluate
马铃薯的生育时期与其它作物不同。根据其无性繁殖的特点,按照茎叶生长和块茎形成过程的相互关系,并结合地上部形态变化,可把马铃薯的生育期划分为芽条生长期、幼苗期、块茎
A number of developed countries are rapidly turning into super-aged societies.Consequently,the demand for reduced surgical invasiveness and enhanced efficiency
Cimicifugae Rhizoma (Sheng ma) is a Ranunculaceae herb belonging to a composite family and well known in China.has been widely used in traditional Chinese medic
5月26日,我的生日。两天前我给第53届威尼斯国际艺术双年展特别机构邀请展——“给马可波罗的礼物”的策展人吕澎写了一份100多字的邮件,表示我愿意为本展览做影像纪录,鉴于
本研究以《国家区试玉米品种一致性及真实性DNA指纹检测技术》(试行稿,2005)和农业部行业标准《玉米品种鉴定DNA指纹方法》(NY/T1432 -2007)为参考,结合本课题组提出的甜、糯玉米SSR分子标记指纹技术,对我国糯玉米区试品种进行DNA检测,综合分析了我国2007年至2009年国家糯玉米区试参试品种的一致性和真实性。结果如下:一致性检测结果表明,3年国家糯玉米区试参试品种中,一致性为好
Peroxisome proliferator activated receptors(PPARs) α,-γ and-β/δ are ligand-activated transcription factors and members of the superfamily of nuclear hormone
冀特2号由河北省农科院谷子研究所采用系统选育的方法培育而成,由于小米食味品质优良,在我国夏谷品种中首次育成一级优质米。1990年3月河北省品审会,以名优特品种破格通过,
Dissolving microneedles carried drug molecules can effectively penetrate the stratum coeum of skin to improve the transdermal drug delivery. The traditional Chi