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髂骨嵴活检不仅显示与年龄相关的小梁骨体积减少,而且也显示与年龄相关的微结构改变,这种改变可以引起小梁骨的连续性丧失。这两个因素可以造成随年龄增加的小梁骨的明显丧失。在负重的小梁骨中(如椎体的中央部分),小梁骨网架呈极度的各向异性——网架中的垂直柱很粗厚,而水平柱很薄。因之,与年龄相关的椎体小梁骨的改建可导致严重的小梁骨丧失。作者以前发现椎体小梁骨的各向异性随年龄而增加,此外还发现随年龄的增加,骨强
The iliac crest biopsy not only shows a reduction in the age-related trabecular bone volume but also age-related microstructural changes that can cause loss of continuity of the trabecular bone. Both of these factors can cause a significant loss of trabecular bone with age. Trabecular meshwork is extremely anisotropic in a weighted trabecular bone (such as the central part of the vertebral body) - the vertical column in the grid is thick and the horizontal column thin. Therefore, the age-related reconstruction of vertebral trabecular bone can lead to severe trabecular bone loss. The authors previously found that the anisotropy of vertebral trabecular bone increased with age, in addition also found that with age, bone strength