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目的探讨个体化131I(131碘)治疗青少年甲亢相关问题及对策。方法18岁以下青少年甲亢患者87例,分两组131I治疗组39例;ATD(抗甲状腺药物)治疗组48例。分别进行疗效比较、突眼治疗的比较、治疗后甲低发生率的比较以及治愈后复发率的比较。结果131I组39例患者治愈27例(69.23%),好转8例(20.51%),无效4例(10.36%);ATD组48例患者治愈22例(45.83%),好转15例(31.25%),无效10例(20.83%)。发生突眼及突眼缓解率两组治疗无明显差异,131I治疗甲低发生率高于ATD治疗,治愈后甲亢复发率低于ATD治疗。结论个体化131I治疗青少年甲亢疗效良好优于ATD治疗,131I治疗青少年甲亢是一种比较有效的方法,但不是首选方法。
Objective To explore the related problems and countermeasures of 131I (131I) treatment of adolescent hyperthyroidism. Methods 87 patients with hyperthyroidism under 18 years of age were divided into two groups of 131I treatment group of 39 cases; ATD (Antithyroid drugs) treatment group of 48 cases. Respectively, the efficacy of comparison, the treatment of exophthalmos compared the incidence of hypothyroidism after treatment and the comparison of the recurrence rate after cure. Results In the 131I group, 39 cases were cured in 27 cases (69.23%), improved in 8 cases (20.51%) and ineffective in 4 cases (10.36%). In ATD group, 48 cases were cured (45.83% , Invalid in 10 cases (20.83%). There was no difference between the two groups in the treatment of exophthalmos and exophthalmos. The incidence of hypothyroidism in 131I treatment was higher than that in ATD treatment, and the recurrence rate of hyperthyroidism after treatment was lower than that of ATD treatment. Conclusion Individualized 131I treatment of hyperthyroidism in children with better efficacy than ATD treatment, 131I treatment of adolescent hyperthyroidism is a more effective method, but not the preferred method.