论文部分内容阅读
本研究通过对脑梗塞核心家系的分析,探讨了遗传因素在核心家系成员中所起作用的程度,结果表明:病例核心家系脑梗塞家族史的比例显著高于对照,X~2=18.41,P<0.001,不同血缘亲属均有不同程度的脑梗塞患病率,从0.93%到12.84%,病例组各亲属中,不论男女和年龄,SMR 均明显高于正常人群的100,经统计学 Z 检验有极显著意义,病例核心家系的 RR、AR和调整率也明显较高,进一步说明血缘关系与脑梗塞之间有较强的联系,RR 高达4.34～6.10,而对照组的 SMR、RR、AR 和调整率似与血缘无关。
In this study, by analyzing the nuclear pedigrees of cerebral infarction, we explored the extent to which genetic factors play a role in the nuclear family members. The results showed that the proportion of family history of cerebral infarction family members was significantly higher than that of the controls (X ~ 2 = 18.41, P <0.001, different blood relatives have different degrees of cerebral infarction prevalence, from 0.93% to 12.84%, relatives of the case group, regardless of age and gender, male and female, SMR were significantly higher than the normal population of 100, the statistical Z test The RR, AR, and adjustment rate of the nuclear family members were also significantly higher, further illustrating that there is a strong relationship between blood relationship and cerebral infarction with RR as high as 4.34 to 6.10, while the SMR, RR, AR of the control group And adjust the rate seems unrelated to blood.