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近年来,脂质过氧化作用已成为一个十分活跃的研究领域,本文拟对脂质过氧化作用机制和由此引起的细胞损害与肝脏疾病,以及抗氧化剂对肝细胞的保护作用作一扼要介绍。一、有关自由基和脂质过氧化作用的基本概念有机化合物分子中的化学键大多数为共价键,在化学反应中,共价键的断裂方式分为两种,一种为异裂,即断裂后共用电子对变为单方所占有,形成阴阳离子,如水在通常条件下电离为氢离子和氢氧根离子。
In recent years, lipid peroxidation has become a very active field of research, this article intends to lipid peroxidation mechanism and the resulting cell damage and liver disease, and antioxidants on the protective effect of liver cells are briefly introduced . First, the basic concepts of free radicals and lipid peroxidation Organic compounds in most of the chemical bonds in the covalent bond, in the chemical reaction, the covalent bond breaking is divided into two kinds, one for the different cracking, that is, After the break, the common electron pair becomes unilaterally occupied, forming anions and cations, such as water ionizing to hydrogen ions and hydroxide ions under normal conditions.