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目的观察酚妥拉明佐治小儿(不完全性)肠梗阻的临床疗效。方法武威市凉州医院儿科2012年6月至2015年6月收治80例确诊为(不完全)肠梗阻的住院患儿,随机分为对照组和观察组各40例。对照组给予禁食水、胃肠减压、补液、灌肠等综合治疗,观察组在此治疗基础上加用酚妥拉明,观察两组病例治疗后临床症状改善情况及恢复时间。结果观察组48h、72h、4~6d治愈率分别为37.5%(15/40)、95.0%(38/40)、100.0%(40/40),对照组分别为20.0%(8/40)、70.0%(28/40)、82.5%(33/40)。观察组在治疗72h和4~6d的治愈率显著高于对照组,差异有统计学意义(P<0.05)。结论酚妥拉明佐治小儿(不完全性)肠梗阻在临床症状恢复及缩短病程方面明显高于对照组,且安全有效,值得在儿科临床上推广应用。
Objective To observe the clinical efficacy of phentolamine in infantile (incomplete) intestinal obstruction. Methods Wuzhou Liangzhou Hospital pediatric June 2012 to June 2015 admitted 80 cases of children diagnosed as (incomplete) intestinal obstruction, were randomly divided into the control group and the observation group of 40 cases. The control group was given fasting water, gastrointestinal decompression, rehydration, enema and other comprehensive treatment, the observation group on the basis of this treatment plus phentolamine, observed two groups of patients after treatment to improve the clinical symptoms and recovery time. Results The cure rates in observation group at 48h, 72h and 4 ~ 6d were 37.5% (15/40), 95.0% (38/40) and 100.0% (40/40) respectively in the observation group and 20.0% (8/40) in the control group 70.0% (28/40), 82.5% (33/40). The cure rate of the observation group at 72h and 4 ~ 6d was significantly higher than that of the control group (P <0.05). Conclusion The incomplete intestinal obstruction in phentolamine was significantly higher than that of the control group in recovering and shortening the course of clinical symptoms and was safe and effective. It is worth to be popularized and applied in pediatrics.