干扰素系统是非特异性免疫系统的重要组成部分。干扰素作为先天性免疫系统的关键因子,在鱼类抵抗病毒感染中发挥了非常重要的作用。近年来,鱼类干扰素系统研究得到了迅速的发展。本文介绍了鱼类I型和II型干扰素及其受体、干扰素调节因子、JAK-STAT信号途径、干扰素诱导蛋白等的研究进展。 The interferon system is an important part of the nonspecific immune system. Interferons, as a key factor in the innate immune system, play a very important role in fish resistance to viral infections. In recent years, the research of fish interferon system has been rapidly developed. This article describes the research progress of fish type I and type II interferons and their receptors, interferon regulatory factors, JAK-STAT signaling pathways, interferon-induced proteins and so on.