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目的通过分析安氏Ⅱ类1分类先证者与其亲代间的相似性,找出亲子间的相关规律,并以此初步认识错畸形的遗传特征。方法对61名安氏Ⅱ类1分类错先证者及其父母共181人的109项头影测量指标分别进行亲子间多元相关分析。结果(且)安氏 Ⅱ类1分类错亲子间骨骼部有相关关系的测量较牙部为多,相关系数也较大;(2)先证者的性别对其与亲代相关关系没有影响。(3)不同性别的亲代,其与子代间相关关系密切程度随研究部位不同而变化:骨骼、软组织部,母亲与子代相关性强;牙部,父亲与子代相关性强。可能与样本量稍小有关。(4)不同年龄的子代,其与亲代相关关系稍有不同。结论安氏Ⅱ类1分类错患者亲子间有明显相似,可能是遗传与环境共同作用的结果,且很可能遗传因素对骨骼部影响较大,而环境因素主要影响牙部。
Objective To find out the correlation between parent-child relationship by analyzing the similarity between Class Ⅱ division 1 probands and their parents, and to understand the genetic characteristics of the malformation deformity. Methods A total of 109 Cephalometric indexes of 61 class Ⅱ division 1 malocclusion probands and 181 parents were analyzed by multivariate correlation analysis. Results (And) Class Ⅱ Division 1 malformations skeletal relatives between the parent-child measurement than the Ministry of teeth is more, the correlation coefficient is larger; (2) the proband’s gender has no effect on the relationship between their parents . (3) The close relatives of offspring with different sexes vary with the study site: the skeletal and soft tissue department, the mother and the offspring have strong relativity; the dental department, the father and the offspring have strong relativity. May be related to the smaller sample size. (4) children of different ages, their relationship with the parent slightly different. Conclusions There is a significant similarity between parents and children in Class Ⅱ division 1 malocclusion. It may be the result of the interaction between heredity and environment. And it is probable that the genetic factors have a great influence on the skeletal division, while the environmental factors mainly affect the dentition.