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目的探索获得性免疫缺陷综合征(AIDS)患者相关消化系统疾病的发生率、临床表现、发病机制及诊断。方法对1000例共用针具静脉注射海洛因者进行问诊、体检及理化检查,按美国疾病预防控制中心CEC诊断标准筛选出CD4+T淋巴细胞<400／μl、人类免疫缺陷病毒(HIV)载量>400拷贝／ml并有消化系统损害的72例作为观察对象。结果 AIDS相关消化系统疾病发生率为1．4％- 98．6％不等,其中口咽部和胃肠道病变71例(98．6％),肝胆胰病变59例(81．9％)。主要表现为发热、腹泻、进行性消瘦、持续性全身淋巴结病、机会性感染、恶性病变、多器官多系统损害。结论 AIDS相关消化系统疾病主要由HIV直接损害、机会性感染、肿瘤及免疫病理损害所致。
Objective To explore the incidence, clinical manifestation, pathogenesis and diagnosis of related digestive diseases in patients with Acquired Immune Deficiency Syndrome (AIDS). Methods A total of 1000 cases of common needles were injected intravenously with heroin for physical examination, physical examination and physical examination. According to the diagnostic criteria of CEC, CD4 + T lymphocytes <400 / μl, human immunodeficiency virus (HIV) > 400 copies / ml and digestive system damage in 72 cases as observed. Results The prevalence of AIDS related digestive diseases ranged from 1.4% to 98.6%. Among them, 71 cases (98.6%) of oropharyngeal and gastrointestinal lesions and 59 cases (81.9%) of hepatobiliary and pancreatic lesions . Mainly for fever, diarrhea, progressive weight loss, persistent generalized lymphadenopathy, opportunistic infections, malignant lesions, multiple organ damage and multiple systems. Conclusion The diseases related to AIDS-related digestive system are mainly caused by the direct damage of HIV, opportunistic infection, tumor and immunopathological damage.