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报道溴莫普林及甲氧苄啶与磺胺甲口恶唑、磺胺嘧啶联合应用和Ａｕｇｍｅｎｔｉｎ对临床常见分离的２０种５０２株菌抗菌作用结果。结果显示：溴莫普林与磺胺药物以１４配比浓度联合应用对多数测试菌具有明显的抗菌协同作用，尤其对大肠埃希氏杆菌、肺炎克雷伯氏菌、伤寒沙门氏菌、沙雷氏菌、柠檬酸杆菌、产气杆菌、阴沟肠杆菌、金葡球菌、化脓性链球菌、肺炎双球菌、奈瑟氏淋球菌、厌氧脆弱拟杆菌等均具有显著的抗菌协同作用。协同率达６０％～１００％，联合用药后抗菌作用比单独用药增效数倍至数百倍。
The antibacterial activity of 20 kinds of 502 strains of bacteria isolated from clinoproxil and brommentol and trimethoprim in combination with sulfamethoxazole and sulfadiazine and Augmentin were reported. The results showed that the combination of brimobole and sulfa drugs with 14 concentrations of the concentration of the test strains have significant antibacterial synergies, especially against Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Serratia , Citrobacter, Aerobacter aerogenes, Enterobacter cloacae, Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Neisseria gonorrhoeae, Bacteroides fragilisAnd so on have significant antibacterial synergy. Synergistic rate of 60% to 100%, the combined antibacterial effect than the drug alone several times to several hundred times.