论文部分内容阅读
目的探讨原发性宫颈腺癌合并内膜浸润的临床病理特点、诊断及其鉴别诊断。方法对1例原发宫颈合并内膜浸润的腺癌进行光镜观察结合免疫组化进行分析。结果宫颈原发腺癌表现为阴道流血和排血性液,镜下腺体密集,排列紊乱,部分呈实体巢状或筛孔状,细胞异型明显。免疫组化:CEA、P63、P53、P16阳性,ER、PR、Vimentin、bcl-2、CA125均阴性,Ki-67 15%~20%。结论原发宫颈腺癌组织类型较多,主要与宫颈腺体良性病变及与邻近脏器原发同类型癌相鉴别。且宫颈腺癌的预后相对差。
Objective To investigate the clinicopathological features, diagnosis and differential diagnosis of primary cervical adenocarcinoma with endometrial invasion. Methods A primary cervical adenocarcinoma with endometrial infiltration was observed by light microscopy and immunohistochemistry. Results The primary cervical adenocarcinoma of the cervix showed vaginal bleeding and effusion. The glandular glands were densely arranged and disordered. Some of them were nested or sieved, and the cells were abnormal. Immunohistochemistry: CEA, P63, P53, P16 positive, ER, PR, Vimentin, bcl-2, CA125 were negative, Ki-67 15% to 20%. Conclusion The primary cervical adenocarcinoma tissue types, mainly with benign cervical lesions and the adjacent organs of the same type of cancer differentiated. And the prognosis of cervical adenocarcinoma is relatively poor.