论文部分内容阅读
目的:观察峨参石油醚、氯仿、乙酸乙酯和正丁醇部位提取物对肺癌细胞A549和H460增殖的抑制作用。方法:应用MTT比色法检测不同部位、不同浓度峨参提取物对肺癌细胞A549和H460增殖的抑制作用。结果:10～1000μg/mL的4个部位峨参提取物对体外培养的人肺癌细胞A549和H460的增殖具有抑制作用,其中石油醚部位、氯仿部位和乙酸乙酯部位提取物抑制作用更明显。结论:峨参不同部位提取物对肺癌细胞增殖具有明显的抑制作用。
OBJECTIVE: To observe the inhibitory effects of extracts of petroleum ether, chloroform, ethyl acetate and n-butanol on the proliferation of lung cancer A549 and H460 cells. Methods: MTT colorimetric assay was used to detect the inhibitory effects of extracts of Anthriscus stenopipes at different sites and concentrations on the proliferation of lung cancer A549 and H460 cells. Results: The extracts of Apostichopus japonicus at concentration of 10 ~ 1000μg / mL had inhibitory effects on the proliferation of human lung cancer cell lines A549 and H460 cultured in vitro. The inhibition of extracts of petroleum ether, chloroform and ethyl acetate was more obvious. Conclusion: The extracts from different parts of Anthriscus spp. Had a significant inhibitory effect on the proliferation of lung cancer cells.