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氯压定即Clonidine(2〔(2,6-二氯苯基)-氨基〕-2-咪唑啉),是临床上无太大副作用,且耐受性较强的一种广泛用于抗高血压的药物。Lal等曾发现,健康人静注氯压定后血浆生长激素浓度增高。有人在鼠及猴子也见到同样现象。本文作者在对一组健康儿童和少年及一组患脑垂体功能减退症的儿童和少年单独口服氯压定后,测定了血浆生长激素浓度的变化。两组对照检查结果表明,用口服氯压定来测定儿童和少年生长激素储备力,方法简便而可靠。
Clonidine (2 [(2,6-dichlorophenyl) -amino] -2-imidazoline is one of the most widely used anti-high Blood pressure medication. Lal et al have found that healthy people after intravenous injection of clonidine increased plasma growth hormone levels. Some people see the same phenomenon in rats and monkeys. The authors measured changes in plasma growth hormone concentrations after a single oral dose of clonidine was administered to a group of healthy children and adolescents and a group of children and adolescents with hypopituitarism. The results of the two control tests showed that the method of determination of growth hormone in children and adolescents with oral chlorine pressure determination method is simple and reliable.