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应用放射免疫技术对50例宫颈癌患者及24例非恶性肿瘤患者的宫颈粘液及外周血CEA的含量进行了测定,结果:宫颈癌患者宫颈粘液CEA测定值及阳性率明显高于对照组(P<0.05,P<0.01)。良、恶性病变的宫颈粘液CEA均明显高于外周血中CEA含量(P<0.01,P<0.02)。而宫颈癌患者血CEA测定值及阳性率与对照组比较均无差异(P>0.05)。宫颈癌患者治疗前、后宫颈粘液CEA测定值差异有显著性(P<0.01)。作者认为:宫颈粘液CEA的测定对宫颈癌的诊断及疗效评价较血CEA的测定更有意义。
Cervical mucosa and peripheral blood CEA levels in 50 cases of cervical cancer and 24 cases of non-malignant tumor were measured by radioimmunoassay. Results: CEA and positive rate of cervical mucus in patients with cervical cancer were significantly higher than those in control group (P <0.05, P <0.01). Cervical mucus CEA in benign and malignant lesions was significantly higher than that in peripheral blood (P <0.01, P <0.02). Cervical cancer patients with serum CEA measured values and positive rates compared with the control group were no significant difference (P> 0.05). Cervical cancer patients before and after treatment of cervical mucus CEA measured values were significantly different (P <0.01). The authors believe that: the determination of cervical mucus CEA cervical cancer diagnosis and efficacy evaluation of blood CEA more meaningful.