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周围血红细胞数量增多可见于多种情况。其中继发的、有原因可查的红细胞增多必须和真性红细胞增多症鉴别,后者是一种原发的血细胞增殖性疾病。真性红细胞增多症主要发生在中年和老年人(尽管在青年甚至在儿童有少数报告),而且它是一个获得性疾病。70年前首先在一个家族中发现几例先天性红细胞增多症患者,以后又报告了几个同样的病例,因此认为是家族性红细胞增生疾病。1965年Cha-rache等首先把这种遗传性红细胞增多症提到分子水平上来认识。他们报告了一个家族性红细胞增多
Increased number of peripheral red blood cells can be found in a variety of situations. Which secondary, there are reasons to check the polycythemia polycythemia must be identified, which is a primary blood cell proliferative disease. Polycythemia vera occurs primarily in middle-aged and older adults (although there are few reports in young people even in children) and it is an acquired disease. Several cases of congenital polycythemia were found in a family 70 years ago and several similar cases were reported later, and are therefore considered to be familial cases of erythropoietic disease. In 1965, Cha-rache and others first mentioned this hereditary polycythemia molecular level to recognize. They reported a familial erythrocyte increase