高血压时,可引起血小板活化、聚集成为血小板血栓的影响因素包括内皮受损、内皮活性物质释放、内皮所生成的具有抗血小板聚集功能的NO减少,以及血小板自身的活化、血小板内源性NO生成减少等。它们相互交织、相互促进,共同导致血小板血栓的形成。在临床治疗中选择性地应用具有抗血小板聚集的抗高血压药物,有望改善血小板的易聚性。 Hypertension, can cause platelet activation, aggregation factors that affect platelet thrombosis include endothelial damage, release of endothelium, endothelium with anti-platelet aggregation function of NO reduction, and platelet activation itself, platelet endogenous NO Generate reduction and so on. They are intertwined, promote each other, together lead to the formation of platelet thrombosis. The selective use of antihypertensives with anti-platelet aggregation in clinical treatment is expected to improve platelet aggregation.