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韧带样瘤是一种深部筋膜或肌腱膜结构来源的低度恶性的纤维性肿瘤,发病率较低。腹壁外和腹壁韧带样瘤的治疗以外科手术为主。首选切缘2cm以上的广泛根治性切除,确保切缘阴性;无法达广泛切除或切缘阴性时,首选保全功能性手术。切缘阳性、复发性患者或无法手术者可考虑辅助放疗。腹腔内韧带样瘤多见于家族结肠腺瘤息肉病患者,手术切除复发率高,目前推荐首选大剂量的三苯氧胺和舒林酸治疗。由于韧带样瘤自然病程多变,药物治疗等疗效多不确切,包含观察等待的个体化治疗方案有望成为韧带样瘤的一种新的治疗模式。
Ligamentous neoplasm is a low-grade fibrous tumor with deep fascia or aponeurotic membrane structure with a low incidence. Abdominal wall and abdominal wall ligament-like tumor treatment based surgery. Preferred radical excision of more than 2cm radical radical excision to ensure that the negative margins; can not reach the broad excision or negative margins, the preferred preservation of functional surgery. Positive margins, recurrent patients or those who can not surgery may consider adjuvant radiotherapy. Intra-abdominal ligament-like more common in patients with familial adenoma polyposis, surgical resection recurrence rate is high, the recommended preferred high-dose tamoxifen and sulindac treatment. As the natural course of ligament-like tumor changes, the efficacy of medical treatment and more uncertainties, including waiting to observe the individualized treatment program is expected to become a new treatment of ligament-like tumor model.