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[目的]:探索炎性乳腺癌的诊断和治疗.[方法]:10例经病理或细胞学检查确诊的炎性乳腺癌先给2~3个周期的CAF(阿霉素+环磷先胺+氟尿嘧啶)方案化疗,然后行总量的2/3量的乳腺及同侧腋窝的放射治疗,放疗结束后休息2周即行乳癌根治切除术,术后切口愈合后再给剩余1/3量的放射治疗,照射胸壁及同侧腋窝和锁骨上使放射总量达到60~70 Gy/野,在放疗前后穿插化疗(CAF)4个周期.[结果]:1例患者未完成治疗出院后1个月死亡.9例患者完成上述序惯治疗,全部病例乳腺红肿、高张消退,乳腺内肿块及同侧腋窝淋巴结明显缩小.手术切除标本检查有5例乳腺内找到癌灶,其中典型炎性癌1例、单纯癌2例、硬癌2例,4例乳腺组织内未找到癌灶.同侧腋窝淋巴结见癌转移7例,同侧锁骨上淋巴结见癌转移2例.生存时间1~28个月,中位生存时间12个月.[结论]:炎性乳腺癌通过序惯治疗可以提高治疗的有效性、延长生命,提高生存质量.
[Objective] To explore the diagnosis and treatment of inflammatory breast cancer. [Method]: 10 cases of inflammatory breast cancer diagnosed by pathology or cytology were given 2-3 cycles of CAF (doxorubicin + cyclophosphamide + Fluorouracil) chemotherapy, and then the total amount of 2/3 of the total amount of breast and ipsilateral axillary radiotherapy, radiotherapy after the end of rest for 2 weeks that radical resection of breast cancer, postoperative wound healing and then give the remaining one third of the amount of Radiotherapy, chest wall irradiation and ipsilateral armpit and supraclavicular bone make the total radiation reach 60 ~ 70 Gy / field, radiotherapy before and after 4 cycles of interspersed chemotherapy (CAF). [Results]: 1 patient discharged after unfinished treatment 1 Month .9 patients completed the order of treatment, all cases of breast swelling, hypervolemosis, intra-breast mass and ipsilateral axillary lymph nodes was significantly reduced. Surgical resection specimens were found in 5 cases of breast cancer foci, including the typical inflammatory cancer 1 case, simple carcinoma in 2 cases, hard carcinoma in 2 cases, 4 cases of breast tissue were not found in the lesion ipsilateral axillary lymph node metastasis in 7 cases, ipsilateral supraclavicular lymph node metastasis in 2 cases, the survival time of 1 to 28 Month, the median survival time of 12 months. [Conclusion]: Inflammatory breast cancer can be used to improve the treatment of Resistance, prolong life and improve quality of life.